' 
![]()
SCIENTIFIC SCORE
Questionable
Based on 15 Researches
6.9
USERS' SCORE
Good
Based on 5 Reviews
8.5
Supplement Facts
Serving Size: 2 Tablets
Amount Per Serving
%DV
Calcium (elemental) (from 2,775 mg complex of Calcium Carbonate, Calcium Citrate, Calcium Ascorbate)
1 g (1,000 mg)
77%
Magnesium (elemental) (from 928 mg complex of Magnesium Oxide, Magnesium Citrate, Magnesium Ascorbate)
500 mg
119%
Top Medical Research Studies
9
Magnesium implantation improves heart recovery
Magnesium implantation as a continuous hydrogen production generator for the treatment of myocardial infarction in rats.
Direct effect on MI treatment
We explored the potential of magnesium implantation as a new approach to combat heart attacks, specifically myocardial infarction (MI). Our research centered on using magnesium slices implanted under the skin of rats to generate hydrogen gas continuously. This method could ensure a greater and longer-lasting concentration of hydrogen directly reaching the heart, which is crucial for its therapeutic effects.
Through our study, we measured how effectively the magnesium produced hydrogen and evaluated its safety. The results were promising; we observed that magnesium implantation not only improved cardiac function in rats suffering from MI, but also played a role in eliminating harmful free radicals from mitochondrial dysfunction. Furthermore, it helped reduce cell death in heart muscle cells, which is a common consequence of heart attacks.
Compared to traditional hydrogen inhalation, which has limitations in delivering sufficient doses over time, magnesium implantation proved to be a superior method. Overall, our findings pave the way for innovative treatments that could enhance recovery after heart attacks by harnessing the unique properties of magnesium for hydrogen production.
Through our study, we measured how effectively the magnesium produced hydrogen and evaluated its safety. The results were promising; we observed that magnesium implantation not only improved cardiac function in rats suffering from MI, but also played a role in eliminating harmful free radicals from mitochondrial dysfunction. Furthermore, it helped reduce cell death in heart muscle cells, which is a common consequence of heart attacks.
Compared to traditional hydrogen inhalation, which has limitations in delivering sufficient doses over time, magnesium implantation proved to be a superior method. Overall, our findings pave the way for innovative treatments that could enhance recovery after heart attacks by harnessing the unique properties of magnesium for hydrogen production.
Read More
8
Magnesium enhances heart attack recovery
Targeted delivery of black phosphorus nanosheets by ROS responsive complex hydrogel based on angiogenesis and antioxidant promotes myocardial infarction repair.
Addresses magnesium's role in MI
We explored an innovative approach to treating myocardial infarction (MI) by using a special composite hydrogel that incorporates magnesium-modified black phosphorus nanosheets. This treatment aims to address the significant changes in the heart's environment after a heart attack, which are usually detrimental to recovery.
The research involved creating a hydrogel scaffold that allows for the gradual release of these magnesium-enhanced nanosheets directly at the site of the infarct. This is particularly important because sustained release helps to manage oxidative stress and inflammation, both common issues following a heart attack.
We observed that the black phosphorus nanosheets have a high reactivity with reactive oxygen species (ROS), which helps reduce oxidative stress and inflammation in the heart. Additionally, the magnesium contributes to promoting blood vessel growth, or angiogenesis, which is crucial for long-term heart function after an MI.
Overall, the findings of this study suggest that the combination of these elements in the hydrogel can effectively block further damage from the heart attack and improve recovery outcomes, signaling a promising avenue for heart attack treatments in the future.
The research involved creating a hydrogel scaffold that allows for the gradual release of these magnesium-enhanced nanosheets directly at the site of the infarct. This is particularly important because sustained release helps to manage oxidative stress and inflammation, both common issues following a heart attack.
We observed that the black phosphorus nanosheets have a high reactivity with reactive oxygen species (ROS), which helps reduce oxidative stress and inflammation in the heart. Additionally, the magnesium contributes to promoting blood vessel growth, or angiogenesis, which is crucial for long-term heart function after an MI.
Overall, the findings of this study suggest that the combination of these elements in the hydrogel can effectively block further damage from the heart attack and improve recovery outcomes, signaling a promising avenue for heart attack treatments in the future.
Read More
7
Magnesium levels linked to CIN
The Role of Magnesium Levels in the Progression of Contrast-Induced Nephropathy in Patients With STEMI Undergoing Primary PCI.
Significant risk factor outlined
We investigated the role of magnesium in the development of contrast-induced nephropathy (CIN) following primary percutaneous coronary intervention (pPCI) in patients suffering from ST-Elevation Myocardial Infarction (STEMI). In our study involving over 2,300 STEMI patients, we found that 30% developed CIN after their procedure. Analyzing the magnesium levels present at admission, we observed that those who experienced CIN had significantly lower magnesium levels compared to those who didn't.
Our findings revealed that magnesium levels below 2.03 mg/dL were linked to an increased risk of developing CIN, alongside other factors like age over 68 years and reduced left ventricular function. We identified this magnesium cutoff through rigorous analysis, demonstrating that low levels of this mineral can be a significant indicator of risk in heart attack patients following a procedure. This insight emphasizes the potential importance of monitoring magnesium levels to help predict and possibly prevent CIN in these vulnerable patients.
Our findings revealed that magnesium levels below 2.03 mg/dL were linked to an increased risk of developing CIN, alongside other factors like age over 68 years and reduced left ventricular function. We identified this magnesium cutoff through rigorous analysis, demonstrating that low levels of this mineral can be a significant indicator of risk in heart attack patients following a procedure. This insight emphasizes the potential importance of monitoring magnesium levels to help predict and possibly prevent CIN in these vulnerable patients.
Read More
Most Useful Reviews
9.5
Reduced heart issues
I found this magnesium very effective. I had a severe deficiency, which led to cramps and spasms, including my heart, causing it to beat irregularly. After the first pill, I noticed immediate peace, and my heartbeat improved significantly. Within three to four days, all deficiency symptoms vanished. The only downside is the large tablets, which can be difficult to take.
Read More
9.5
Cured gout attacks
I used to suffer from gout attacks three times a year but since taking this supplement, I haven't had a single seizure. I've also shared it with friends, and they’ve had the same success. It’s truly remarkable.
Read More
9.5
Heart symptoms relieved
I had heart problems, and my doctor recommended magnesium. After a week or two, my symptoms disappeared completely. I experienced no side effects and will continue taking it, as women need magnesium too. I highly recommend it!
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 15 Researches
6.9
9
Calcium's role in heart regeneration
Pharmacological or genetic inhibition of LTCC promotes cardiomyocyte proliferation through inhibition of calcineurin activity.
Moderate clarity on calcium's effects
We explored how calcium signaling influences heart cell proliferation, particularly after injuries like heart attacks. Our study centered on the L-Type Calcium Channel (LTCC) and how its inhibition might help heart cells regenerate. Remarkably, when we inhibited LTCC—either through pharmacological means or by enhancing the activity of an inherent inhibitor called RRAD—we observed significant boosts in heart cell activity.
This process appears connected to calcineurin activity, a key player in cell signaling. By carefully manipulating these pathways, we managed to not only provoke heart cell growth in lab settings but also improve heart function and reduce scar tissue in live animal models post-heart attack.
Through our findings, we highlight the potential for new calcium-related treatments that could significantly benefit patients with heart injury, paving the way for exciting advancements in regenerative medicine. By understanding this intricate relationship between calcium signaling and heart cell growth, we open doors for innovative therapies that could transform recovery strategies in cardiovascular care.
This process appears connected to calcineurin activity, a key player in cell signaling. By carefully manipulating these pathways, we managed to not only provoke heart cell growth in lab settings but also improve heart function and reduce scar tissue in live animal models post-heart attack.
Through our findings, we highlight the potential for new calcium-related treatments that could significantly benefit patients with heart injury, paving the way for exciting advancements in regenerative medicine. By understanding this intricate relationship between calcium signaling and heart cell growth, we open doors for innovative therapies that could transform recovery strategies in cardiovascular care.
Read More
9
Magnesium implantation improves heart recovery
Magnesium implantation as a continuous hydrogen production generator for the treatment of myocardial infarction in rats.
Direct effect on MI treatment
We explored the potential of magnesium implantation as a new approach to combat heart attacks, specifically myocardial infarction (MI). Our research centered on using magnesium slices implanted under the skin of rats to generate hydrogen gas continuously. This method could ensure a greater and longer-lasting concentration of hydrogen directly reaching the heart, which is crucial for its therapeutic effects.
Through our study, we measured how effectively the magnesium produced hydrogen and evaluated its safety. The results were promising; we observed that magnesium implantation not only improved cardiac function in rats suffering from MI, but also played a role in eliminating harmful free radicals from mitochondrial dysfunction. Furthermore, it helped reduce cell death in heart muscle cells, which is a common consequence of heart attacks.
Compared to traditional hydrogen inhalation, which has limitations in delivering sufficient doses over time, magnesium implantation proved to be a superior method. Overall, our findings pave the way for innovative treatments that could enhance recovery after heart attacks by harnessing the unique properties of magnesium for hydrogen production.
Through our study, we measured how effectively the magnesium produced hydrogen and evaluated its safety. The results were promising; we observed that magnesium implantation not only improved cardiac function in rats suffering from MI, but also played a role in eliminating harmful free radicals from mitochondrial dysfunction. Furthermore, it helped reduce cell death in heart muscle cells, which is a common consequence of heart attacks.
Compared to traditional hydrogen inhalation, which has limitations in delivering sufficient doses over time, magnesium implantation proved to be a superior method. Overall, our findings pave the way for innovative treatments that could enhance recovery after heart attacks by harnessing the unique properties of magnesium for hydrogen production.
Read More
9
Magnesium scaffolds improve heart attack outcomes
Outcomes of the two generations of bioresorbable scaffolds (Magmaris vs. Absorb) in acute coronary syndrome in routine clinical practice.
Study indicates magnesium benefits
We examined the performance of two types of bioresorbable scaffolds in patients experiencing acute coronary syndrome (ACS) - a common and serious manifestation of heart disease. Specifically, we compared the effectiveness of magnesium-based scaffolds, known as Magmaris, with the earlier polymer scaffolds called Absorb.
Our study included 193 patients using Magmaris and 160 patients using Absorb, all treated in similar clinical settings. Over the course of one year, we monitored their health outcomes, particularly focusing on serious issues like cardiac death, heart attacks, and instances of scaffold thrombosis.
Surprisingly, we found that patients with Magmaris had significantly better outcomes than those with Absorb. Specifically, the rates of primary complications and target lesion failures were notably lower with Magmaris. We noted a concerning trend with Absorb, where patients experienced a higher rate of scaffold thrombosis.
Overall, our findings suggest that magnesium-based scaffolds could provide a safer and more effective option for patients undergoing treatment for heart attacks compared to their polymer counterparts.
Our study included 193 patients using Magmaris and 160 patients using Absorb, all treated in similar clinical settings. Over the course of one year, we monitored their health outcomes, particularly focusing on serious issues like cardiac death, heart attacks, and instances of scaffold thrombosis.
Surprisingly, we found that patients with Magmaris had significantly better outcomes than those with Absorb. Specifically, the rates of primary complications and target lesion failures were notably lower with Magmaris. We noted a concerning trend with Absorb, where patients experienced a higher rate of scaffold thrombosis.
Overall, our findings suggest that magnesium-based scaffolds could provide a safer and more effective option for patients undergoing treatment for heart attacks compared to their polymer counterparts.
Read More
8
Magnesium enhances heart attack recovery
Targeted delivery of black phosphorus nanosheets by ROS responsive complex hydrogel based on angiogenesis and antioxidant promotes myocardial infarction repair.
Addresses magnesium's role in MI
We explored an innovative approach to treating myocardial infarction (MI) by using a special composite hydrogel that incorporates magnesium-modified black phosphorus nanosheets. This treatment aims to address the significant changes in the heart's environment after a heart attack, which are usually detrimental to recovery.
The research involved creating a hydrogel scaffold that allows for the gradual release of these magnesium-enhanced nanosheets directly at the site of the infarct. This is particularly important because sustained release helps to manage oxidative stress and inflammation, both common issues following a heart attack.
We observed that the black phosphorus nanosheets have a high reactivity with reactive oxygen species (ROS), which helps reduce oxidative stress and inflammation in the heart. Additionally, the magnesium contributes to promoting blood vessel growth, or angiogenesis, which is crucial for long-term heart function after an MI.
Overall, the findings of this study suggest that the combination of these elements in the hydrogel can effectively block further damage from the heart attack and improve recovery outcomes, signaling a promising avenue for heart attack treatments in the future.
The research involved creating a hydrogel scaffold that allows for the gradual release of these magnesium-enhanced nanosheets directly at the site of the infarct. This is particularly important because sustained release helps to manage oxidative stress and inflammation, both common issues following a heart attack.
We observed that the black phosphorus nanosheets have a high reactivity with reactive oxygen species (ROS), which helps reduce oxidative stress and inflammation in the heart. Additionally, the magnesium contributes to promoting blood vessel growth, or angiogenesis, which is crucial for long-term heart function after an MI.
Overall, the findings of this study suggest that the combination of these elements in the hydrogel can effectively block further damage from the heart attack and improve recovery outcomes, signaling a promising avenue for heart attack treatments in the future.
Read More
8
Magnesium improves heart recovery
Magnesium lithospermate B enhances the potential of human-induced pluripotent stem cell-derived cardiomyocytes for myocardial repair.
Study evaluates magnesium's effects.
In our investigation, we set out to understand how magnesium lithospermate B (MLB) can aid heart repair following a heart attack. We used a mouse model with surgically induced myocardial infarction (MI) and categorized the mice into five groups, including those treated with MLB and human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). By comparing different treatments, we evaluated the heart's recovery over four weeks through echocardiography and histochemical staining.
Our findings revealed that MLB significantly enhances the function of hiPSC-CMs, helping to repair the damaged heart muscle. This improvement happens by boosting the function of endothelial cells—important for blood vessel health—through a specific signaling pathway. Additionally, MLB decreases apoptosis, or cell death, in hiPSC-CMs by activating another pathway, which further supports heart recovery.
Overall, our work underscores the role of MLB in improving heart repair after a heart attack. While it was tested in tandem with hiPSC-CMs, which makes it an interesting combination for treatment strategies, it's clear that the integration of MLB can potentially enhance cardiac recovery mechanisms effectively.
Our findings revealed that MLB significantly enhances the function of hiPSC-CMs, helping to repair the damaged heart muscle. This improvement happens by boosting the function of endothelial cells—important for blood vessel health—through a specific signaling pathway. Additionally, MLB decreases apoptosis, or cell death, in hiPSC-CMs by activating another pathway, which further supports heart recovery.
Overall, our work underscores the role of MLB in improving heart repair after a heart attack. While it was tested in tandem with hiPSC-CMs, which makes it an interesting combination for treatment strategies, it's clear that the integration of MLB can potentially enhance cardiac recovery mechanisms effectively.
Read More
User Reviews
USERS' SCORE
Good
Based on 5 Reviews
8.5
9.5
Reduced heart issues
I found this magnesium very effective. I had a severe deficiency, which led to cramps and spasms, including my heart, causing it to beat irregularly. After the first pill, I noticed immediate peace, and my heartbeat improved significantly. Within three to four days, all deficiency symptoms vanished. The only downside is the large tablets, which can be difficult to take.
Read More
9.5
Cured gout attacks
I used to suffer from gout attacks three times a year but since taking this supplement, I haven't had a single seizure. I've also shared it with friends, and they’ve had the same success. It’s truly remarkable.
9.5
Heart symptoms relieved
I had heart problems, and my doctor recommended magnesium. After a week or two, my symptoms disappeared completely. I experienced no side effects and will continue taking it, as women need magnesium too. I highly recommend it!
8.8
Heart health improvement
At first, I experienced pain and discomfort, but soon everything stabilised, leading to improved indicators for my heart and nerves. I noted no side effects during my intake.
3.8
Essentials for heart
Calcium is crucial for bone health and helps prevent osteoporosis, while magnesium is beneficial for high blood pressure and heart disease.
